Tooth and gum discomfort is frequently experienced during orthodontic treatments, including those using clear aligners. This pain is often most acute when a new aligner is first introduced. Acetaminophen (Tylenol) is recommended over ibuprofen (Advil) for managing pain during orthodontic treatment.
While over-the-counter pain relievers can alleviate this discomfort, it’s important to choose the right type. Research, including a notable 1996 study, has shown that some medications may actually hinder the movement of teeth. In this study, orthodontic devices were tested to observe the effects of various pain relievers. The findings indicated that ibuprofen (Advil) significantly reduced tooth movement. Although aspirin and naproxen were not specifically tested in this study, they are part of the same NSAID family as ibuprofen and might similarly impede orthodontic progress. On a positive note, acetaminophen (Tylenol) did not impact tooth movement, making it a safer choice for managing pain during orthodontic adjustments.
For further details, refer to the study by Michael J. Kehoe, Steven M. Cohen, Kourosh Zarrinnia, and Alan Cowan in the October 1996 issue of The Angle Orthodontist, which explores the effects of acetaminophen, ibuprofen, and misoprostol on prostaglandin E2 synthesis and orthodontic tooth movement dynamics.